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NEP162
GENERAL CATALOGUE

NEP162

HY-174996 · 50 mg

MedChemExpress · Cat: HY-174996

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medchemexpress.com/nep162.html
Catalog No: HY-174996
CAS No: 3031840-36-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

NEP162 is a BRD4 PROTAC degrader with DC50s of 1.2 and 1.6 ?M in SW480 and U2OS cells. NEP162 exhibits antiproliferative activity, effectively inhibits tumor growth and induces apoptosis. NEP162 can be used for the study of osteosarcoma, colorectal cancer and non-small cell lung cancer, etc. Pink: BRD4 ligand : HY-78695 , Blue: E3 ligase Ligand HY-D2259 , BLACK: Linker, E3 ligase ligand-linker conjugate HY-174997 .

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