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Netarsudil dimesylate
GENERAL CATALOGUE

Netarsudil dimesylate

HY-12798A · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-12798A

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Catalog No: HY-12798A
CAS No: 1422144-42-0
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Netarsudil AR-13324 dimesylate is a competitive inhibitor of Rho-associated protein kinases ROCK I and ROCK II and a reversible inhibitor of the norepinephrine transporter NET . Netarsudil dimesylate reduces intraocular pressure by inhibiting ROCK, causing relaxation of trabecular meshwork cells and dilation of episcleral veins, thereby increasing the ease of aqueous humor outflow, while inhibiting NET to reduce aqueous humor production. Netarsudil dimesylate is mainly used in the study of ocular hypertension and primary open-angle glaucoma.

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