GENERAL CATALOGUE
Netarsudil
HY-12798 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-12798
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Catalog No: HY-12798
CAS No: 1254032-66-0
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Netarsudil AR-13324 is a competitive inhibitor of Rho-associated protein kinases ROCK I and ROCK II and a reversible inhibitor of the norepinephrine transporter NET . Netarsudil reduces intraocular pressure by inhibiting ROCK, causing relaxation of trabecular meshwork cells and dilation of episcleral veins, thereby increasing the ease of aqueous humor outflow, while inhibiting NET to reduce aqueous humor production. Netarsudil is mainly used in the study of ocular hypertension and primary open-angle glaucoma.
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