Neuroglycan C Rabbit Polyclonal Antibody

Description

EnkiLife offers the Neuroglycan C Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,IHC application. Alternative Names of Immunogen: CSPG5; CALEB; NGC; Chondroitin sulfate proteoglycan 5; Acidic leucine-rich EGF-like domain-containing brain protein; Neuroglycan C. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:50-1:300 Background: The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals.,function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.,miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage.,PTM:N-glycosylated.,PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation.,PTM:Phosphorylated; in intracellular and extracellular parts.,similarity:Contains 1 EGF-like domain.,subcellular location:In neurons, localizes to synaptic junctions (By similarity). Also detected in the endoplasmic reticulum and the Golgi (By similarity). Partially enriched in lipid rafts.,subunit:Binds TNR and probably TNC (By similarity). Interacts with ERBB3 and GOPC.,tissue specificity:Restricted to brain (at protein level).,