Neuropeptide AF (cattle)

Description

Neuropeptide AF cattle , an amidated octadecapeptide, is RFamide neuropeptide. Neuropeptide AF cattle acts as a ligand of Mas-related gene receptor A4 MrgprA4 Mas-related G-protein-coupled Receptor MRGPR EC50 of 60 nM and MrgprC11 EC50 of 300 nM . Neuropeptide AF cattle also activate to the G protein-coupled receptors NPFF1 Neuropeptide Y Receptor EC50 of 25-325 nM and NPFF2 EC50 of 1-5 nM . Neuropeptide AF cattle shows anti-opiate and related pain modulation effects.