GENERAL CATALOGUE
NF-?B-IN-14
HY-162004 · 50 mg
MedChemExpress · Cat: HY-162004
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Manufacturer product page
medchemexpress.com/nf-%CE%BAb-in-14.htmlCatalog No: HY-162004
CAS No: 3019972-01-8
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
NF-?B-IN-14 compound 5e significantly inhibits nitric oxide production in LPS-induced macrophages IC50: 6.4 ?M . NF-?B-IN-14 disrupts the TLR4-MyD88 protein interaction, leading to the suppression of the NF-?B signaling pathway suppression. NF-?B-IN-14 reduces ear edema and inflammation in an atopic dermatitis mouse model.