NF-?B/MAPK-IN-1

Name: NF-?B/MAPK-IN-1
Brand: MedChemExpress

HY-147972 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-147972

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medchemexpress.com/nf-%CE%BAb-mapk-in-1.html

Catalog No: HY-147972

CAS No: 2413940-56-2

Category: Immunology Inflammation

Pack Size: Free Sample (0.1 - 0.2 mg)

Brand: MedChemExpress

Description

NF-?B/MAPK-IN-1 compound 11a is a potent inhibitor of NF-?B and MAPK pathway. NF-?B/MAPK-IN-1 shows inhibitory activity against NO production, with an IC50 of 6.96 AAasAasAAmuM. NF-?B/MAPK-IN-1 suppresses LPS-induced iNOS, COX-2, ER? and P38 signaling activation. NF-?B/MAPK-IN-1 can prevent LPS induced inflammatory response in macrophages. NF-?B/MAPK-IN-1 can be used for rheumatoid arthritis RA research.