NFE2 Rabbit Polyclonal Antibody

Description

EnkiLife offers the NFE2 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,ELISA application. Alternative Names of Immunogen: NFE2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000 Background: function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron. similarity:Belongs to the bZIP family. similarity:Belongs to the bZIP family. CNC subfamily. similarity:Contains 1 bZIP domain. subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis. tissue specificity:Expressed in hematopoietic cells and also in colon and testis.