GENERAL CATALOGUE
NHI-2
HY-124309 · 5 mg
MedChemExpress · Cat: HY-124309
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medchemexpress.com/nhi-2.htmlCatalog No: HY-124309
CAS No: 1269802-97-2
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
NHI-2 is a lactate dehydrogenase A LDHA inhibitor with an IC50 of 14.7 AAasAasAAmuM. NHI-2 shows selective for LDHA over LDHB IC50 = 55.8 AAasAasAAmuM . NHI-2 is an efficient anti-glycolytic agent. NHI-2 enhances apoptosis, induces cell cycle arrest at S and G2 phases. NHI-2 has a broad spectrum anti-proliferative activity in cancer cells. NHI-2 affects extracellular acidification rate and ATP production. NHI-2 suppresses tumor growth in murine B78 melanoma tumor model.
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