GENERAL CATALOGUE
Nifurpirinol
HY-135470 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-135470
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medchemexpress.com/nifurpirinol.htmlCatalog No: HY-135470
CAS No: 13411-16-0
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Nifurpirinol P-7138 is a selective prosubstrate of bacterial nitroreductase NTR . NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic ? cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis FSGS .
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