GENERAL CATALOGUE
Nigericin sodium salt
HY-100381 · 5 mg
MedChemExpress · Cat: HY-100381
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Catalog No: HY-100381
CAS No: 28643-80-3
Category: Anti-infection
Pack Size: 5 mg
Brand: MedChemExpress
Description
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH pHi , and inactivation of Wnt/?-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC.
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