GENERAL CATALOGUE
Ninerafaxstat
HY-139577 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139577
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Catalog No: HY-139577
CAS No: 2254741-41-6
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Ninerafaxstat IMB-1018972 is a novel orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat competitively inhibits 3-ketoacyl-CoA thiolase 3-KAT to partially suppress fatty acid oxidation, and shifts cardiac energy metabolism from free fatty acid oxidation to glucose oxidation, regulating myocardial substrate utilization and thereby improving cardiac efficiency. Ninerafaxstat can be used for research on cardiovascular diseases.
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