

HY-139577A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-139577A
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medchemexpress.com/ninerafaxstat-trihydrochloride.htmlDescription
Ninerafaxstat trihydrochloride IMB-1018972 trihydrochloride is the trihydrochloride salt form of Ninerafaxstat HY-139577 . Ninerafaxstat trihydrochloride is a novel orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat trihydrochloride competitively inhibits 3-ketoacyl-CoA thiolase 3-KAT to partially suppress fatty acid oxidation, and shifts cardiac energy metabolism from free fatty acid oxidation to glucose oxidation, regulating myocardial substrate utilization and thereby improving cardiac efficiency. Ninerafaxstat trihydrochloride can be used for research on cardiovascular diseases.







