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Niraparib tosylate hydrate
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Niraparib tosylate hydrate

HY-10619E · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-10619E

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Catalog No: HY-10619E
CAS No: 1613220-15-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Niraparib MK-4827 tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

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