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Nirogacestat dihydrobromide
GENERAL CATALOGUE

Nirogacestat dihydrobromide

HY-15185B · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-15185B

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Catalog No: HY-15185B
CAS No: 1962925-29-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Nirogacestat dihydrobromide PF-3084014 dihydrobromide is a reversible, orally bioavailable, noncompetitive, and selective ?-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat dihydrobromide while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers.

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