GENERAL CATALOGUE
Nirogacestat
HY-15185 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-15185
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medchemexpress.com/PF-3084014.html
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Catalog No: HY-15185
CAS No: 1290543-63-3
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Nirogacestat PF-3084014 is a reversible, orally bioavailable, noncompetitive, and selective ?-secretase inhibitor with an IC50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers.
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