GENERAL CATALOGUE
Nitroaspirin
HY-123823 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-123823
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Manufacturer product page
medchemexpress.com/nitroaspirin.htmlCatalog No: HY-123823
CAS No: 175033-36-0
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Nitroaspirin NCX 4016 is a nitric oxide NO donor and a nitro-derivative of Aspirin, which combines with Nitroaspirin to inhibit cyclooxygenase. Nitroaspirin NCX 4016 has antithrombotic and anti-platelet properties and acts as a direct and irreversible inhibitor of COX-1. Nitroaspirin NCX 4016 causes significant induction of cell cycle arrest and apoptosis in Cisplatin-resistant human ovarian cancer cells via down-regulation of EGFR/PI3K/STAT3 signaling and modulation of Bcl-2 family proteins.
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