GENERAL CATALOGUE
NKH477
HY-103193 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-103193
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Catalog No: HY-103193
CAS No: 138605-00-2
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
NKH477 Colforsin dapropate hydrochloride directly activates the catalytic unit of adenylate cyclase and increases intracellular cAMP. NKH477 is a forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 exerts an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts.
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