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NLRP3-IN-20
GENERAL CATALOGUE

NLRP3-IN-20

HY-156121 · 50 mg

MedChemExpress · Cat: HY-156121

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medchemexpress.com/nlrp3-in-20.html
Catalog No: HY-156121
CAS No: 2428478-22-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress

Description

NLRP3-IN-20 compound 11 is an orally available inhibitor of the NLRP3 inflammasome with an IC50 of 25 nM for IL-1? secretion. NLRP3-IN-20 has excellent pharmacokinetic properties and demonstrated significant efficacy in models of non-alcoholic steatohepatitis, fatal septic shock, and colitis.

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