GENERAL CATALOGUE
NLRP3-IN-49
HY-168089 · 50 mg
MedChemExpress · Cat: HY-168089
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Manufacturer product page
medchemexpress.com/nlrp3-in-49.htmlCatalog No: HY-168089
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
NLRP3-IN-49 compound Z48 is a potent and specific NLRP3 inhibitor IC50=0.26 ?M in THP-1 cells, IC50=0.21 ?M in mouse bone marrow macrophages . NLRP3-IN-49 can directly bind to NLRP3 protein Kd=1.05 ?M , effectively preventing the assembly and activation of NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 can be used in the study of inflammatory bowel disease.
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