GENERAL CATALOGUE
NLRP3-IN-75
HY-170233 · 50 mg
MedChemExpress · Cat: HY-170233
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Manufacturer product page
medchemexpress.com/nlrp3-in-75.htmlCatalog No: HY-170233
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
NLRP3-IN-75 is an orally active NLRP3 inhibitor. NLRP3-IN-75 suppresses IL-1? secretion IC50 = 23 nM . NLRP3-IN-75 selectively inhibits NLRP3 activation by disrupting inflammasome assembly without affecting NLRC4 or AIM2 inflammasomes. NLRP3-IN-75 exhibits superior efficacy in acute peritonitis, diabetic kidney disease and IBD models.
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