GENERAL CATALOGUE
NLRP3-IN-77
HY-171589 · 50 mg
MedChemExpress · Cat: HY-171589
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medchemexpress.com/nlrp3-in-77.htmlCatalog No: HY-171589
CAS No: 2924547-57-7
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
NLRP3-IN-77 Compound 7n is a potent NLRP3 inflammasome inhibitor. NLRP3-IN-77 inhibits the viability of THP-1 cells with an IC50 value of 5.36 nM. NLRP3-IN-77 can effectively reduce the secretion of interleukin-1? IL-1? and interleukin-18 IL-18 . NLRP3-IN-77 is promising for research of diseases related to the abnormal activation of the NLRP3 inflammasome, such as cancer and inflammatory diseases.
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