GENERAL CATALOGUE
NLRP3-IN-8
HY-146594 · 50 mg
MedChemExpress · Cat: HY-146594
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medchemexpress.com/nlrp3-in-8.htmlCatalog No: HY-146594
CAS No: 2768650-56-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
NLRP3-IN-8 compound 27 is an orally active, directly binding NLRP3 inflammasome inhibitor with an IC50 value of 1.23 ?M against IL-1 ?. NLRP3-IN-8 has good metabolic stability to liver microsomes t1/2 = 138.63 min , and has almost no toxicity against L02: IC50 100 ?M.
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