GENERAL CATALOGUE
NLRP3-IN-NBC6
HY-131040 · 1 mg
MedChemExpress · Cat: HY-131040
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Catalog No: HY-131040
CAS No: 2068818-02-8
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor IC50= 574 nM that acts independently of Ca2+. NLRP3-IN-NBC6 inhibits Nigericin HY-127019 -induced inflammasome activation in THP-1 cells and Imiquimod HY-B0180 -induced IL-1? release from LPS-primed bone marrow-derived macrophages BMDMs .
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