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Nocarnickelamide B
GENERAL CATALOGUE

Nocarnickelamide B

HY-N15301 · 50 mg

MedChemExpress · Cat: HY-N15301

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Catalog No: HY-N15301
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

Nocarnickelamide B Compound 2 is a linear peptide and ROCK1/2 inhibitor. Nocarnickelamide B exhibits dual inhibitory activity against ROCK1 and ROCK2 with IC50s of 14.9 ?M and 21.9 ?M, respectively. Nocarnickelamide B binds to the ATP-binding site. Nocarnickelamide B inhibits the activation of ROCK-regulated cytoskeletal contraction markers such as the myosin light chain. Nocarnickelamide B is potential for glaucoma reasearch.

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