

HY-168024 · 50 mg
MedChemExpress · Cat: HY-168024
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medchemexpress.com/nod1-2-in-1.htmlDescription
NOD1/2-IN-1 Compound 18 is a potent RIPK2 inhibitor with an IC50 value of 1.4 nM, as determined by the ADP-Glo assay. NOD1/2-IN-1 blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathways, with IC50 values of 18 nM and 170 nM for NOD1 and NOD2, respectively, thereby reducing inflammatory responses. NOD1/2-IN-1 can be used in studies related to colitis.