GENERAL CATALOGUE
NPC26
HY-169652 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-169652
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medchemexpress.com/npc26.html
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Catalog No: HY-169652
CAS No: 864860-32-2
Category: Epigenetics
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
NPC26 is a small molecule mitochondrial disruptor with anti-tumor activity. NPC-26 shows significant anti-proliferative and cytotoxic effects on CRC cell lines HCT-116, DLD-1, and HT-29 . NPC26 can damage mitochondrial function, leading to the opening of the mitochondrial permeability transition pore mPTP and the production of reactive oxygen species, ultimately inducing cell death. NPC-26 can kill CRC cells by activating the AMP-activated protein kinase AMPK signaling pathway.
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