GENERAL CATALOGUE
NPD-1335
HY-126250 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-126250
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medchemexpress.com/npd1335.htmlCatalog No: HY-126250
CAS No: 2376326-31-5
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NPD1335 is a Trypanosoma brucei phosphodiesterase B1 TbrPDEB1 inhibitor with submicromolar activities against T. brucei parasites. NPD1335 displays a greatly improved cytotoxicity profile. NPD1335 increases intracellular cAMP levels and results in the distortion of the cell cycle and cell death. NPD-1335 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.
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