GENERAL CATALOGUE
NPD10084
HY-148615 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-148615
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Catalog No: HY-148615
CAS No: 1040706-91-9
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NPD10084 is a pyruvate kinase PKM2 inhibitor that inhibits non-glycolytic signaling in cancer cells. NPD10084 disrupts the interaction between PKM2 and ?-catenin or STAT3 and inhibits downstream signaling. NPD10084 has antiproliferative activity against colorectal cancer cells in vitro and in vivo.
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