GENERAL CATALOGUE
NR2F2-IN-1 free base
HY-156190A · 5 mg
MedChemExpress · Cat: HY-156190A
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medchemexpress.com/nr2f2-in-1-free-base.html
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Catalog No: HY-156190A
CAS No: 452087-38-6
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
NR2F2-IN-1 free base is a potent and selective orphan nuclear receptor COUP-TFII NR2F2 inhibitor. NR2F2-IN-1 free base substantially inhibits COUP-TFIIAAasAasAadriven NGFIA reporter expression. NR2F2-IN-1 free base directly binds to the COUP-TFII ligand-binding domain and disrupts COUP-TFII interaction with transcription regulators, including FOXA1, thus repressing COUP-TFII activity on target gene regulation.
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