NRBP Rabbit Polyclonal Antibody

Description

EnkiLife offers the NRBP Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: NRBP1 BCON3 NRBP. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:5000-1:20000 Background: caution:Author states that kinase activity observed in PubMed:11956649 may be due to sample contamination. This protein is predicted to be catalytically inactive. domain:The protein kinase domain is predicted to be catalytically inactive. function:May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. similarity:Contains 1 protein kinase domain. subcellular location:Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia. subunit:Homodimer. Binds to MLF1, recruiting a serine kinase which phosphorylates both itself and MLF1. Phosphorylated MLF1 binds to YWHAZ and is retained in the cytoplasm. tissue specificity:Ubiquitously expressed in all tissues examined with high levels in the testis.