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Nrf2 activator-10
GENERAL CATALOGUE

Nrf2 activator-10

HY-124834 · 100 mg

MedChemExpress · Cat: HY-124834

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Catalog No: HY-124834
CAS No: 75483-04-4
Category: Apoptosis
Pack Size: 100 mg
Brand: MedChemExpress

Description

Nrf2 activator-10 Compound AI-1 is a PI3K-dependent inducer for antioxidant response element ARE EC50 is 2.7 ?M and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.

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