GENERAL CATALOGUE
NSC 617145
HY-110185 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-110185
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medchemexpress.com/nsc-617145.htmlCatalog No: HY-110185
CAS No: 203115-63-3
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NSC 617145 is a selective werner syndrome helicase WRN helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks DSB and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases.
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