GENERAL CATALOGUE
NSC-658497
HY-19539 · 5 mg
MedChemExpress · Cat: HY-19539
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Manufacturer product page
medchemexpress.com/nsc-658497.htmlCatalog No: HY-19539
CAS No: 909197-38-2
Category: GPCR G Protein
Pack Size: 5 mg
Brand: MedChemExpress
Description
NSC-658497 is an effective inhibitor of Ras-GEF, SOS1. NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras, downstream signaling activities, and associated cell proliferation.
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