GENERAL CATALOGUE
NSC 95397
HY-108543 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-108543
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medchemexpress.com/nsc-95397.htmlCatalog No: HY-108543
CAS No: 93718-83-3
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor Ki=32 nM Cdc25A , 96 nM Cdc25B , 40 nM Cdc25C ; IC50=22.3 nM human Cdc25A , 56.9 nM human Cdc25C , 125 nM Cdc25B . NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 MKP-1 and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.
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