GENERAL CATALOGUE
NSC697923
HY-13811 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-13811
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Catalog No: HY-13811
CAS No: 343351-67-7
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NSC697923 is a potent UBE2N ubiquitin-conjugating enzyme E2 N, Ubc13 inhibitor. NSC697923 induces neuroblastoma NB cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-?B signaling. Antitumor activity.
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