GENERAL CATALOGUE
NSC745887
HY-123786 · 50 mg
MedChemExpress · Cat: HY-123786
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Catalog No: HY-123786
CAS No: 54490-26-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
NSC745887 compound 25 is an inhibitor that targets DNA topoisomerase cleavage, activates the caspase-8/9-caspase-3-poly ADP-ribose polymerase cascade, and induces apoptosis in cancer cells. NSC745887 enhances ?H2AX expression and causes DNA fragmentation leading to DNA damage.