GENERAL CATALOGUE
Nsp12-IN-2
HY-174439 · 50 mg
MedChemExpress · Cat: HY-174439
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Catalog No: HY-174439
CAS No: 667882-55-5
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Nsp12-IN-2 Compound 8 , the triphosphate metabolite of 4-thiouridine HY-W113081 , is a SARS-CoV-2 Nsp12 inhibitor. Nsp12-IN-2 inhibits the RNA-dependent RNA polymerase RdRp activity of the SARS-CoV-2 Nsp12-Nsp7-Nsp8 complex, terminates RNA synthesis and also blocks the RNAylation and NMPylation of Nsp9. Nsp12-IN-2 is promising for research of infections caused by SARS-CoV-2, other coronaviruses, and other RNA viruses.
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