NTRK3 Mouse Monoclonal Antibody

Description

EnkiLife offers the NTRK3 Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for ELISA application. Alternative Names of Immunogen: TRKC; gp145(trkC). The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: ELISA 1:5000-1:20000 Background: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.