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NTRK3 Stable Ba/F3 Cell Line
GENERAL CATALOGUE

NTRK3 Stable Ba/F3 Cell Line

T3096 · 1 x 106 cells / 1.0 mL

abm good · Cat: T3096

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Catalog No: T3096
Category: Cellular Materials
Pack Size: 1 x 106 cells / 1.0 mL
Brand: abm good

Description

Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The NTRK3 Stable Ba/F3 Cell Line expresses activated human NTRK3 tyrosine kinase that is linked to a GFP reporter GFP-ETV6-NTRK3 in SED2 vector . Ba/F3 cells expressing activated tyrosine kinase become completely dependent on the kinase activity for survival and as a result, the cells can be propagated even in the absence of IL-3. This cell line carries the SED2 vector which does not have any selection markers.

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