

HY-122038 · 50 mg
MedChemExpress · Cat: HY-122038
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Manufacturer product page
medchemexpress.com/nu-8165.html
Description
NU-8165 is an inhibitor of the MDM2-p53 protein-protein interaction with anti-tumor activity. Optimization of NU-8165 was guided by MDM2 NMR titrations, which indicated key binding interaction regions. NU-8165 activated MDM2 and p21 transcription in cell-based assays and showed modest selectivity for wild-type p53 cell lines.







