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NU-8165
GENERAL CATALOGUE

NU-8165

HY-122038 · 50 mg

MedChemExpress · Cat: HY-122038

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medchemexpress.com/nu-8165.html
Catalog No: HY-122038
CAS No: 849723-20-2
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

NU-8165 is an inhibitor of the MDM2-p53 protein-protein interaction with anti-tumor activity. Optimization of NU-8165 was guided by MDM2 NMR titrations, which indicated key binding interaction regions. NU-8165 activated MDM2 and p21 transcription in cell-based assays and showed modest selectivity for wild-type p53 cell lines.

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