GENERAL CATALOGUE
NU6140
HY-107419 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-107419
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Catalog No: HY-107419
CAS No: 444723-13-1
Category: Cell Cycle DNA Damage
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
NU6140 is a selective CDK2-cyclin A inhibitor IC50, 0.41 ?M , exhibits 10- to 36-fold selectivity over other CDKs. NU6140 also potently inhibits Aurora A and Aurora B, with IC50s of 67 and 35 nM, respectively. Enhances the apoptotic effect, with anti-cancer activity.
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