GENERAL CATALOGUE
Nur77 modulator 4
HY-170849 · 50 mg
MedChemExpress · Cat: HY-170849
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medchemexpress.com/nur77-modulator-4.html
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Catalog No: HY-170849
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Nur77 modulator 4 Compound 15h is a Nur77 inducer with a KD of 0.477 ?M. Nur77 modulator 4 significantly induces Nur77 expression and apoptosis, showing excellent growth inhibition in HepG2 and MCF-7 cells, with an IC50 of less than 5 ?M. Nur77 modulator 4 activates Nur77-mediated ER stress through the PERK-ATF4 and IRE1 signaling pathways, thereby inducing cell apoptosis. Nur77 modulator 4 can be used in cancer research applications .
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