GENERAL CATALOGUE
Nutlin-3a
HY-10029 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10029
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Catalog No: HY-10029
CAS No: 675576-98-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Nutlin-3a Rebemadlin , an active enantiomer of Nutlin-3, is a potent murine double minute MDM2 inhibitor IC50=90 nM . Nutlin-3a inhibits interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas.
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