GENERAL CATALOGUE
NVS-SM2
HY-111520 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-111520
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medchemexpress.com/nvs-sm2.htmlCatalog No: HY-111520
CAS No: 1562333-92-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron SMN protein expression. NVS-SM2 can be used for spinal muscular atrophy SMA research.
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