GENERAL CATALOGUE
O-Desmethyl gefitinib-d8
HY-100064S · 1 mg
MedChemExpress · Cat: HY-100064S
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medchemexpress.com/o-desmethyl-gefitinib-d8.htmlCatalog No: HY-100064S
Category: JAK STAT Signaling
Pack Size: 1 mg
Brand: MedChemExpress
Description
O-Desmethyl gefitinib-d8 is a deuterium labeled O-Desmethyl gefitinib. O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays.