GENERAL CATALOGUE
O-Desmethyl gefitinib
HY-100064 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-100064
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Manufacturer product page
medchemexpress.com/o-desmethyl-gefitinib.htmlCatalog No: HY-100064
CAS No: 847949-49-9
Category: JAK STAT Signaling
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays.