GENERAL CATALOGUE
O6-Benzylguanine
HY-W002585 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-W002585
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medchemexpress.com/o6-benzylguanine.htmlCatalog No: HY-W002585
CAS No: 19916-73-5
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase MGMT/AGT inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity.
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