GENERAL CATALOGUE
OATD-02
HY-155108 · 50 mg
MedChemExpress · Cat: HY-155108
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medchemexpress.com/oatd-02.html
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Catalog No: HY-155108
CAS No: 2146132-73-0
Category: Immunology Inflammation
Pack Size: 50 mg
Brand: MedChemExpress
Description
OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and 2. OATD-02 is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM hARG1 , 39 nM hARG2 , 39 nM mARG1 , and 28 nM rARG1 , respectively. OATD-02 abolishes tumor immunosuppression induced by both arginases. OATD-02 can be used for melanoma study.
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