GENERAL CATALOGUE
OATD-02 hydrochloride
HY-155108B · 1 mg
MedChemExpress · Cat: HY-155108B
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medchemexpress.com/oatd-02-hydrochloride.htmlCatalog No: HY-155108B
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
OATD-02 hydrochloride is the hydrochloride salt form of OATD-02 HY-155108 . OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM hARG1 , 39 nM hARG2 , 39 nM mARG1 , and 28 nM rARG1 , respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study.
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